Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular strand-replacement polymerization on magnetic nanoparticles.

نویسندگان

  • Fenglei Gao
  • Zhu Zhu
  • Jianping Lei
  • Huangxian Ju
چکیده

A novel strategy of dual signal amplification was developed using circular strand-replacement DNA polymerization with a molecular beacon as a switch and silver enhancement on magnetic nanoparticles for the specific Raman spectroscopic detection of DNA down to the sub-picomolar level.

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عنوان ژورنال:
  • Chemical communications

دوره 48 86  شماره 

صفحات  -

تاریخ انتشار 2012